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$110.00
TB-500 is a synthetic analogue of Thymosin Beta-4, a naturally occurring 43-amino-acid protein found in virtually every human and animal cell. X-Fuel TB-500 is supplied at 10mg per vial, lyophilised to ultra-purity research grade. Thymosin Beta-4 is well-established in wound-healing research, and TB-500’s synthetic analogue version has become a staple of the advanced athlete recovery stack — frequently paired with BPC-157 for a synergistic connective tissue and muscle-repair protocol. If BPC-157 works locally, TB-500 is understood to work systemically.
TB-500 10mg — Ultra-Purity Research Grade
What Is TB-500?
TB-500 is a synthetic peptide derived from the active region of Thymosin Beta-4 (Tβ4), specifically the actin-binding domain sequence LKKTETQ. Thymosin Beta-4 is one of the most abundant intracellular peptides in mammalian tissue, involved in cell migration, differentiation, and wound healing. TB-500 isolates and mimics this active segment, making it more practical from a peptide synthesis standpoint.
X-Fuel’s TB-500 is supplied as a 10mg lyophilised vial at ultra-purity research grade — a high-dose format commonly used in performance and recovery research communities.
Why the Community Uses It
TB-500 has built a strong reputation in the advanced athletic community as a systemic healing compound. Unlike BPC-157 (which is often characterised as more locally acting), TB-500 is frequently described as having systemic distribution — meaning it may address healing across multiple tissue sites following a single administration point.
Research interests and community use cases include:
Mechanism of Action
TB-500’s primary mechanism centres on its role in actin sequestration. Actin is a structural protein critical for cell movement and tissue repair. By binding G-actin, Thymosin Beta-4 (and by extension, TB-500) regulates the actin polymerisation process — influencing cell migration to wound sites, blood vessel formation (angiogenesis), and the inflammatory cascade involved in healing.
The BPC-157 + TB-500 Stack
This combination is arguably the most well-known peptide protocol in the performance community. The logic: BPC-157 operates through gastric-derived protective pathways with strong local effects on tendons and gut lining; TB-500 operates through the actin/cell-migration pathway with broader systemic reach. Together they are theorised to address healing from complementary angles. Many users report running both together during an injury recovery phase.
Reconstitution & Storage
Supplied lyophilised. Reconstitute with bacteriostatic water (2mL per vial is a common starting point). Store reconstituted peptide refrigerated at 2–8°C. Use within 28 days of reconstitution. Lyophilised powder stores best refrigerated, away from UV light.
Quality & Purity
X-Fuel TB-500 is manufactured to ultra-purity research-grade standards. Produced via established solid-phase peptide synthesis methods with stringent purity verification.
Storage Information
Lyophilised vial: refrigerate at 2–8°C, keep away from direct light. Once reconstituted: refrigerate, use within 28 days. Do not freeze reconstituted solution.
Usage & Reconstitution
Reconstitute with 2mL bacteriostatic water per vial (yielding 5mg/mL). Add BAC water slowly along the vial wall. Do not shake — allow to dissolve naturally.
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