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Somatropin is recombinant human growth hormone — the 191-amino acid polypeptide that is structurally identical to what your pituitary produces. It directly activates GH receptors, triggers IGF-1 production, drives anabolic signalling via mTOR, and promotes lipolysis in adipose tissue. For research into the full GH-IGF-1 axis — as opposed to secretagogues that stimulate endogenous GH release — somatropin is the direct tool. True North Peptides supplies somatropin at 15IU per vial. For research use only.
What Is Somatropin?
Somatropin is recombinant human growth hormone (rhGH) — produced via recombinant DNA technology to be structurally identical to endogenous pituitary GH. It’s a 191-amino acid, 22kDa polypeptide that directly binds GH receptors and activates the JAK2-STAT5 signalling cascade. The downstream result: hepatic IGF-1 production, muscle protein synthesis upregulation, adipose lipolysis, and a range of metabolic and regenerative effects that make it one of the most researched hormones in sports science and anti-ageing biology.
Somatropin vs Secretagogues (Ipamorelin, Tesamorelin)
This is an important distinction. Somatropin is exogenous GH — you’re providing the hormone directly. Secretagogues like ipamorelin (GHSR agonist) and tesamorelin (GHRH analogue) stimulate the pituitary to produce and release its own GH. The research implications differ: somatropin lets you study GH receptor signalling directly; secretagogues let you study the GH release pathway. Many advanced research protocols examine both.
GH-IGF-1 Axis — The Anabolic Cascade
GH acts on the liver to drive IGF-1 production. IGF-1 then activates the PI3K-Akt-mTOR pathway — the primary driver of muscle protein synthesis, cell growth, and tissue repair. Research into this axis covers body composition (muscle accrual, fat loss), wound healing and recovery, metabolic health, and the counter-regulatory effects of GH on insulin action.
Storage & Handling
Reconstitute with bacteriostatic water by injecting slowly down the vial wall. Swirl gently — never shake. Protein aggregation and loss of biological activity result from shaking. Store reconstituted solution at 2–8°C.
Product Specifications
Compound: Somatropin (recombinant human growth hormone, 191 AA) | Vial Size: 15IU | Form: Lyophilised powder | Purity: Research-grade | Storage: −20°C dry; 2–8°C post-reconstitution.
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